The synaptic structure of PACAP immunoreactive axons in the intermediolateral nucleus of the rat.
Neurosci Lett
; 214(1): 65-8, 1996 Aug 16.
Article
in En
| MEDLINE
| ID: mdl-8873133
ABSTRACT
Immuno-electronmicroscopic studies were performed to detect the presence and features of synaptic contacts between pituitary adenylate cyclase activating polypeptide immunoreactive (PACAP-ir) axons and cholera toxin B-horseradish peroxidase labeled preganglionic sympathetic neurons (PSNs) in the intermediolateral nucleus of the rat thoracic spinal cord. PACAP-ir axon varicosities, which contained small clear and large core synaptic vesicles, were found to form asymmetric type of synaptic contacts with dendrites and infrequently with somata of labeled preganglionic neurons. The present study provides ultrastructural evidence of PACAP-ir synaptic contacts with PSNs, raising the possibility that the peptide may function as a transmitter/modulator to these neurons.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spinal Cord
/
Axons
/
Synapses
/
Neuropeptides
Limits:
Animals
Language:
En
Journal:
Neurosci Lett
Year:
1996
Document type:
Article
Affiliation country:
Japón