Synthesis and pharmacological activity of some N,N-disubstituted 1-amino-2-phenyl-3H,12H-naphtho[1,2-b]pyrano[2,3-d]pyran-3-ones.
Farmaco
; 51(10): 665-8, 1996 Oct.
Article
in En
| MEDLINE
| ID: mdl-8981757
ABSTRACT
The synthesis of some N,N-disubstituted 1-amino-2-phenyl-3H,12H-naphtho[1,2-b]pyrano[2,3-d]pyran-3-ones 4, by reaction of phenylchloroketene with a series of N,N-disubstituted 3-aminomethylene-2,3-dihydro-4H-naphtho[1,2-b]pyran-4-ones, followed by dehydrochlorination in situ of the primary adducts with DBN, is described. Some compounds 4 showed antiarrhythmic and analgesic activities.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anti-Arrhythmia Agents
/
Naphthols
Language:
En
Journal:
Farmaco
Journal subject:
FARMACOLOGIA
/
QUIMICA
Year:
1996
Document type:
Article
Affiliation country:
Italia