Structure of a kinetic protein folding intermediate by equilibrium amide exchange.
Nat Struct Biol
; 4(10): 801-4, 1997 Oct.
Article
in En
| MEDLINE
| ID: mdl-9334744
ABSTRACT
A combination of equilibrium amide exchange and kinetic folding data show that the essential features of the complex topology of the N-terminal domain of a thermophilic phosphoglycerate kinase are established on a millisecond or faster timescale, before the rate-limiting step in the folding pathway commences.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phosphoglycerate Kinase
/
Protein Structure, Secondary
/
Protein Folding
Language:
En
Journal:
Nat Struct Biol
Journal subject:
BIOLOGIA MOLECULAR
Year:
1997
Document type:
Article