Developmental changes in UDP-N-acetylglucosamine 2-epimerase activity of rat and guinea-pig liver.
Comp Biochem Physiol B Biochem Mol Biol
; 118(1): 13-5, 1997 Sep.
Article
in En
| MEDLINE
| ID: mdl-9417989
ABSTRACT
The activity of UDP-N-acetylglucosamine 2-epimerase was determined in the liver of rats and guinea-pigs of different ages. The activity of this enzyme in rats was low at birth, increased to a maximum value on day 15, and fell gradually until day 30. Thereafter, it increased up to the 60th day. The activity profile of the enzyme from guinea-pig liver was very similar. However, guinea-pig activity was 2-5 times lower than in rats. Both rats and guinea-pigs displayed similar liver sialic acid contents which increased from birth to 2 months of age. Rats also showed a N-glycolylneuraminic acid content that decreased from birth to 2 months. From these results we can inferred that postnatal UDP-N-acetylglucosamine 2-epimerase activity seems to be correlated with age and the developmental states of rats and guinea-pigs.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Escherichia coli Proteins
/
Liver
Limits:
Animals
Language:
En
Journal:
Comp Biochem Physiol B Biochem Mol Biol
Journal subject:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
Year:
1997
Document type:
Article
Affiliation country:
España