Transformation of some pyrido[2,3-d]pyrimidine derivatives into other di- and triheterocyclic systems.
Farmaco
; 52(11): 657-62, 1997 Nov.
Article
in En
| MEDLINE
| ID: mdl-9550090
ABSTRACT
It was stated that three analogous ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-5-carboxylates (7-9) react with hydrazine hydrate giving derivatives of the new heterocyclic system pyrido[2,3,4-ef]pyridazino[3,4-e]-1,2,4-triazepine (10-12), pyrido[3,4-d]pyridazine (16-18) and pentaazaphenalene (13-15). The latters were formed in low yields. The results of the preliminary pharmacological study of 2 of these compounds are reported.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pyrimidines
Limits:
Animals
Language:
En
Journal:
Farmaco
Journal subject:
FARMACOLOGIA
/
QUIMICA
Year:
1997
Document type:
Article
Affiliation country:
Polonia