Minor cerebral alterations observed by magnetic resonance imaging in syndromic children with mental retardation.
Eur J Radiol
; 27(2): 139-44, 1998 May.
Article
in En
| MEDLINE
| ID: mdl-9639139
ABSTRACT
OBJECTIVE:
To evaluate the anomalies of the central nervous system (CNS) by magnetic resonance imaging (MRI) in normal subjects and in syndromic patients. METHODS ANDMATERIAL:
Seventy-three normal subjects and 50 different syndromic patients with mental retardation (from 3 months to 16 years) were studied utilizing several morphometric parameters (degree of myelination of the white matter, evaluation of liquoral spaces, septo-caudate distance, Evans index, Aboulezz method, and length, width and angles of corpus callosum).RESULTS:
A high frequency of anomalies of the corpus callosum, the Chiari anomaly and alterations either of the white matter or of the ventricular and periencephalic system have been observed.CONCLUSION:
The authors point out the importance of cerebral MRI in the study of CNS in patients with malformation syndromes. The present research, carried out on a large number of both normal subjects and patients with malformation syndromes, represents one of the first systematic studies in this field.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain
/
Intellectual Disability
Type of study:
Observational_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Eur J Radiol
Year:
1998
Document type:
Article
Affiliation country:
Italia