Effects of neural stem cells and 5-fluorocytosine in canine metastatic lung tumor
Journal of Veterinary Science
; : 257-260, 2017.
Article
in En
| WPRIM
| ID: wpr-109771
Responsible library:
WPRO
ABSTRACT
This is the first case report to describe the tumor regressive effect of systemic human neural stem cell (NSC)/5-fluorocytosine (5-FC) therapy on canine metastatic lung tumor. The therapeutic effects appeared approximately two weeks after 5-FC administration. Thoracic radiographs revealed a reduced number of lung nodules and decreased nodule size. However, there were no significant antitumor effects on primary lesions in abdominal organs. In conclusion, human NSC/5-FC prodrug therapy can secure patient quality of life with the same or more therapeutic effects and fewer side effects than other recommended chemotherapies.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Quality of Life
/
Genetic Therapy
/
Therapeutic Uses
/
Drug Therapy
/
Neural Stem Cells
/
Flucytosine
/
Lung
Aspects:
Patient_preference
Limits:
Humans
Language:
En
Journal:
Journal of Veterinary Science
Year:
2017
Document type:
Article