Case of a Spindle Cell Metaplastic Carcinoma of the Breast

ABSTRACT

A metaplastic carcinoma of the breast is a histologically diverse type of malignancy in which an adenocarcinoma is found to co-exist with an admixture of spindle cell, squamous, chondroid, or bone-forming neoplastic cells. Metaplastic breast cancer is rare and accounts for less than 1% of all mammary tumors. An adenocarcinoma with spindle cell metaplasia is one of the least often recognized variants of a metaplastic carcinoma. The clinical behavior of this variant of metaplastic carcinoma has not yet been clearly defined. Herein, we report a case of spindle cell metaplastic carcinoma of the breast. We also present a review of the literature.