The Prognostic Impact of Obstructed Colorectal Cancer
Journal of the Korean Society of Coloproctology
; : 479-486, 2008.
Article
in Ko
| WPRIM
| ID: wpr-222672
Responsible library:
WPRO
ABSTRACT
PURPOSE:
An obstructed colorectal cancer (OB) has a poorer survival than a non-obstructed cancer (NOB). This study examined the prognostic impact of bowel obstruction on colorectal cancer.METHODS:
From December 1999 to December 2005, patients undergoing single stage operation for OB were examined prospectively. OB (n= 193) was compared with a NOB (n=444) used in a primary tumor resection during the same period. 637 colorectal cancers were examined in this study.RESULTS:
The overall operative mortality was 21 (3.3%) and the postoperative mortality was significantly higher in the OB (OB 16, 8.3%) group than in the NOB (NOB 5, 1.1%) group. The proportion of OB was higher in the left-colon (52.8%) than in the right colon (16.0%) and rectum (31.1%, P<0.001). However, OB was associated with an older age (P=0.013). The proportion of advanced tumor stage was higher in OB (II 35.8%, III 39.5%, IV 24.7%) than in NOB (II 53.2%, III 35.8%, IV 11.0%, P<0.001). The 5-year cancer-related survival for OB was worse than NOB (OB 77.3%, NOB 57.8%, P<0.05). However, in the cases of a colorectal cancer performed curative resection (stage II and III), the survival for OB was not worse than NOB stage II (OB 82.8%, NOB 92.2%, P=0.24), stage III (OB 65.2%, NOB 56.9%, P=0.43).CONCLUSIONS:
OB has older and more advanced disease characteristics. However, if an oncologically curative resection is performed, the survival for OB is similar to that of a NOB.Key words
Full text:
1
Database:
WPRIM
Main subject:
Rectum
/
Colorectal Neoplasms
/
Prospective Studies
/
Colon
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Humans
Language:
Ko
Journal:
Journal of the Korean Society of Coloproctology
Year:
2008
Document type:
Article