Study on etiology of clinically diagnosed non A-E hepatitis / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 7-10, 2002.
Article
in Zh
| WPRIM
| ID: wpr-355139
Responsible library:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>To study etiology of clinically diagnosed non A-E hepatitis.</p><p><b>METHODS</b>HBV, TTV, human parvovirus B19, SENV DNA were detected by nested polymerase chain reactions (nPCR), while HGV, HCV RNA were tested by reverse transcription nested polymerase chain reactions (RT-nPCR).</p><p><b>RESULTS</b>Of 60 patients with clinically diagnosed non A-E hepatitis, 30 (50.0%) were HBV DNA positive alone, 10 (16.7%) HBV and TTV DNA positive, 6 (10.0%) HBV and B19 DNA positive; 1 (1.7%) HBV, SENV DNA and HCV RNA positive, 1 (1.7%) HCV RNA positive alone, 1 (1.7%) HCV RNA and B19 DNA positive, 2 (3.3%) B19 DNA positive alone, 1 (1.7%) TTV DNA positive alone, and the remaining 8 (13.3%) negative for all viruses. All the 60 patients were HGV RNA negative. There were no differences in serum biochemical markers of hepatitis B patients with or without TTV or B19 virus infection.</p><p><b>CONCLUSIONS</b>HBV is a major etiologic agent for the clinically diagnosed non A-E hepatitis. HGV, TTV, B19 and SEBV may not be associated with nonA-E hepatitis.</p>
Full text:
1
Database:
WPRIM
Main subject:
Virology
/
Blood
/
DNA, Viral
/
RNA, Viral
/
Hepatitis B virus
/
Sequence Analysis, DNA
/
Hepacivirus
/
Diagnosis
/
Genetics
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Hepatitis B
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Adult
/
Aged
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Female
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Humans
/
Male
Language:
Zh
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2002
Document type:
Article