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MicroRNA-mediated Tumor Multidrug Resistance and Function of Traditional Chinese Medicine / 世界科学技术-中医药现代化
Article in Zh | WPRIM | ID: wpr-440860
Responsible library: WPRO
ABSTRACT
MicroRNA (miRNA for short) can induce mRNA cleavage or inhibit mRNA translation and regulate gene expression in the post-transcriptional level, which involves cell development, proliferation, differentiation, apoptosis, and a series of important biological processes. Recent studies have found that the abnormal regulation of miRNA's target genes may be involved in tumor resistance. And it is expected to become important tumor resistance-associat-ed molecular markers and therapeutic targets. Mechanism of traditional Chinese medicine (TCM) and its active ingre-dients can affect miRNA to regulate target proteins and target genes mediated tumor multidrug resistance. It can pro-vide new ideas for the mechanism of reversing multidrug resistance by TCM.
Key words
Full text: 1 Database: WPRIM Language: Zh Journal: World Science and Technology-Modernization of Traditional Chinese Medicine Year: 2013 Document type: Article
Full text: 1 Database: WPRIM Language: Zh Journal: World Science and Technology-Modernization of Traditional Chinese Medicine Year: 2013 Document type: Article