Research progress of patient-derived xenograft model / 国际外科学杂志
International Journal of Surgery
; (12): 50-52, 2015.
Article
in Zh
| WPRIM
| ID: wpr-470958
Responsible library:
WPRO
ABSTRACT
Tumor cell line culture technologies emerged as a strong impetus to the development of tumor biology research.However,cell line tumor model presented limited predictive value and instable properties in the clinical translational research of new cancer therapies.Recently Patient-derived Xenograft Model (PDX) has aroused researcher's attention and been widely applied to new cancer therapy research.This new model could highly retain the stroma heterogeneity、histological characteristics and molecular diversity of the original tumor,and is expected to bring new breakthroughs in individualized treatment of tumor patients.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
International Journal of Surgery
Year:
2015
Document type:
Article