Endoscopic ultrasonography combined with magnifying endoscopy with narrow band imaging for the diagnostic value of early colorectal cancer / 肿瘤研究与临床

ABSTRACT

Objective To investigate the diagnostic value of endoscopic ultrasonography combined with magnifying endoscopy with narrow band imaging (NBI-ME) in the diagnosis of early colorectal cancer.Methods A total of 187 patients with early colorectal cancer who were treated in Cancer Hospital Chinese Academy Medical Sciences and Peking Union Medical College from January 2015 to December 2017 were retrospectively analyzed.The patients were examined with NBI-ME along with endoscopic ultrasonography before endoscopic or surgical treatment,and the depth of invasion was judged.Finally,postoperative pathology was taken as the gold standard to evaluate the value of endoscopic ultrasonography combined with NBI-ME in the diagnosis of early colorectal cancer.Results The histopathological results were treated as the golden standard.The diagnostic accuracy rate of endoscopic ultrasonography and endoscopic ultrasonography combined with NBI-ME in 187 patients with early colorectal cancer was 84.0 ％ (157/187),92.5 ％ (173/187)respectively.Overall accuracy rate of the invasive depth of NBI-ME in the patients with early colorectal cancer was 87.2 ％ (166/187).Sensitivity of endoscopic ultrasonography combined with NBI-ME to Tm,Tsml and ≥Tsm2 in early colorectal cancer pathological tissues was 92.4 ％,90.4 ％,93.3 ％ respectively,and the corresponding specificity was 93.9 ％,90.1％,90.9 ％ respectively.The diagnostic accuracy rate of endoscopic ultrasonography combined with NBI-ME was higher than that of endoscopic ultrasonography,and there was a significant difference (x2 =6.594,P =0.010 2).Conclusion Endoscopic ultrasonography combined with NBI-ME has a high accuracy rate for evaluating the depth of invasion in early colorectal cancer,which contributes to a good application value for preoperative evaluation of early colorectal cancer.