Sinonasal Teratocarcinosarcoma, a Rare Tumor Involving Boththe Nasal Cavity and the Cranial Cavity

ABSTRACT

Sinonasal teratocarcinosarcoma (SNTCS), a very rare tumor, is known to be a heterogeneous with epithelial,mesenchymal, and neuroepithelial components and shows a very aggressive clinical course. Dueto the heterogeneity of this tumor, it is often misdiagnosed. No definitive treatment modality has been reportedbecause it is a very rare tumor. A 44-year-old man presented to a rhinologist with headache andnasal obstruction, and an intranasal tumor was found that invaded into the cranial cavity. He underwentcombined surgery with a rhinologist and a neurosurgeon following cognitive decline that worsened aftera transnasal biopsy. The patient was diagnosed with SNTCS and underwent radiotherapy. However, residualtumor was found during radiotherapy and additional chemotherapy was administered. Follow-upbrain MRI revealed no remnant or recurrent lesion. SNTCS is a tumor that has not yet been well researchedand should be further investigated for proper treatment.