Circular RNA and its role in liver diseases / 解剖学报

ABSTRACT

The circular RNA (circ RNA) is a novel non-coding RNA having no 5' end cap structure and a 3' end poly(A) tail, and is a reversely linked closed loop structure formed by non-covalent bonds. Due to its role as a sponge for miRNA molecules and biomarker, circular RNA can be used in the treatment and diagnosis of liver diseases, and it has increasingly become a research hotspot. In this paper, the research on circRNA and circRNA in liver disease is reviewed, in order to provide theoretical basis and new ideas for the research and treatment of future liver diseases.