The role and action mechanism of signaling proteins in the occurrence and development of neuroblastoma / 国际药学研究杂志
Journal of International Pharmaceutical Research
; (6): 576-581, 2019.
Article
in Zh
| WPRIM
| ID: wpr-845262
Responsible library:
WPRO
ABSTRACT
Neuroblastoma(NB)is the most common extracranial solid tumor derived from the sympathetic ner- vous system in childhood. The location of NB is variable, the pathogenesis is complex and the clinical manifestations vary greatly. The prognosis is good in low or medium risk NB patients but bad in high risk NB patients. Recent studies have shown that the occurrence, growth, proliferation, migration and invasion of NB as well as the prognosis of NB pa- tients are associated with the abnormal expression of signaling proteins in NB, including the transcriptional regulators, kinases, and receptors, etc.. This article reviews the role and action mechanism of different signaling proteins in the oc- currence and development of NB.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
Journal of International Pharmaceutical Research
Year:
2019
Document type:
Article