Research advances in the role of ion channels genetics in autism spectrum disorders / 中华实用儿科临床杂志

ABSTRACT

Autism spectrum disorder (ASD) are kind of developmental behavior disorders with the core symptoms of social communication disorders, stereotyped behavior and narrow interest.Genetic factors play an important role in the incidence of ASD.Ion channels are a pore-forming protein on biofilm.They allow certain types of ions to pass through, and help to establish the voltage difference between cytoplasmic membranes, acting as the basis of neuroelectrophysiology.Ion channel abnormalities are related to many diseases, including ASD.In this paper, several kinds of genes related to ASDs in ion channels were reviewed, and in order to provide new ideas in the pathogenesis.