Natural ingredients from Chinese materia medica for pulmonary hypertension / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 801-814, 2021.
Article
in En
| WPRIM
| ID: wpr-922763
Responsible library:
WPRO
ABSTRACT
Pulmonary hypertension (PH) is a severe pathophysiological condition characterized by pulmonary artery remodeling and continuous increases in pulmonary artery pressure, which may eventually develop to right heart failure and death. Although newly discovered and incredible treatment strategies in recent years have improved the prognosis of PH, limited types of effective and economical drugs for PH still makes it as a life-threatening disease. Some drugs from Chinese materia medica (CMM) have been traditionally applied in the treatment of lung diseases. Accumulating evidence suggests active pharmaceutical ingredients (APIs) derived from those medicines brings promising future for the prevention and treatment of PH. In this review, we summarized the pharmacological effects of APIs derived from CMM which are potent in treating PH, so as to provide new thoughts for initial drug discovery and identification of potential therapeutic strategies in alternative medicine for PH.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Drugs, Chinese Herbal
/
Materia Medica
/
China
/
Hypertension, Pulmonary
/
Medicine, Chinese Traditional
Type of study:
Diagnostic_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2021
Document type:
Article