Mycophenolate Mofetil for Treatment of Autoimmune Hemolytic Anemia and Nephrotic Syndrome after Cord Blood Transplantation / 대한수혈학회지

ABSTRACT

We report on a 2-year-old girl who developed autoimmune hemolytic anemia, which occurred with minimal change nephrotic syndrome 3 months after umbilical cord blood transplantation for acute megakaryocytic leukemia. Because the disease is regarded as chronic graft versus host disease and developed while taking cyclosporine medication, she was treated with methylprednisolone 2 mg/kg/day. However, hemolysis and proteinuria were refractory to steroid treatment. One week after starting methylprednisolone, mycophenolate mofetil was added. Hemolysis and proteinuria showed improvement after 2 weeks of mycophenolate mofetil medication.