Advances on myeloid-derived suppressor cells in hepatitis B virus infection / 中华临床感染病杂志
Chinese Journal of Clinical Infectious Diseases
; (6): 234-240, 2023.
Article
in Zh
| WPRIM
| ID: wpr-993736
Responsible library:
WPRO
ABSTRACT
Myeloid-derived suppressor cells (MDSCs) are a group of immature and heterogeneous cells that can inhibit T cell function. In pathological conditions such as tumors, infections, and chronic inflammation, the large expansion of MDSCs is involved in processes of immune escape, immune tolerance and inflammatory reactions. MDSCs are also crucial in the pathophysiology of hepatitis B virus (HBV) infection, however, their activation, differentiation, and function during HBV infection are still unclear. This article reviews the general characteristics and roles of MDSCs in HBV infection, as well as related drug therapies, in order to provide information for further research on the related mechanism and potential targeted treatment.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Clinical Infectious Diseases
Year:
2023
Document type:
Article