The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen
Braz. J. Pharm. Sci. (Online)
; 54(4): e18008, 2018. tab
Article
in English
| LILACS
| ID: biblio-1001592
Responsible library:
BR40.1
Localization: BR40.1
ABSTRACT
The objective of the study was to evaluate the use of human albumin in a Brazilian university hospital, in compliance with the institutional protocol and other clinical guidelines, taking into account the therapeutic indications and the dosage regimens. Data was obtained from the pharmacy dispensing records of human albumin, the requests for use it and, when available, the patient's records between January and October 2017. After evaluation the therapeutic indications and the dosage regimens were classified as "appropriate" and "inappropriate". The analysis of 98 requests showed that, when compared to the institutional protocol, 54 (55.1%) requests had an inappropriate therapeutic indication. However, when a comparison was made between 25 medical records (54 requests) and other clinical guidelines, it was observed that the therapeutic indication had none classified as inappropriate. In addition, 16 (29.7%) requests were considered inappropriate in relation to dosage regimens. From these results, it was possible to conclude that although the use of human albumin in the hospital was associated to a clinical protocol, it was outdated. Thus, it is possible to affirm that not only the adoption of a clinical protocol, but its periodical updating is an important strategy to promote the rational use of drugs.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Posology
/
Therapeutic Uses
/
Serum Albumin, Human
/
Hospitals, University
Type of study:
Practice guideline
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. J. Pharm. Sci. (Online)
Journal subject:
Farmacologia
/
Teraputica
/
Toxicologia
Year:
2018
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Sao Paulo/BR
/
University Hospital of University of Sao Paulo/BR