Brazilian guidelines for the management of psychomotor agitation. Part 2. Pharmacological approach
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
; 41(4): 324-335, July-Aug. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1011506
Responsible library:
BR1.1
ABSTRACT
Objective:
To present the essential guidelines for pharmacological management of patients with psychomotor agitation in Brazil.Methods:
This is a systematic review of articles retrieved from the MEDLINE (PubMed), Cochrane Database of Systematic Reviews, and SciELO databases published from 1997 to 2017. Other relevant articles in the literature were also used to develop these guidelines. The search strategy used structured questions formulated using the PICO model, as recommended by the Guidelines Project of the Brazilian Medical Association. Recommendations were summarized according to their level of evidence, which was determined using the Oxford Centre for Evidence-based Medicine system and critical appraisal tools.Results:
Of 5,362 articles retrieved, 1,731 abstracts were selected for further reading. The final sample included 74 articles that met all inclusion criteria. The evidence shows that pharmacologic treatment is indicated only after non-pharmacologic approaches have failed. The cause of the agitation, side effects of the medications, and contraindications must guide the medication choice. The oral route should be preferred for drug administration; IV administration must be avoided. All subjects must be monitored before and after medication administration.Conclusion:
If non-pharmacological strategies fail, medications are needed to control agitation and violent behavior. Once medicated, the patient should be monitored until a tranquil state is possible without excessive sedation. Systematic review registry number CRD42017054440.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Psychomotor Agitation
/
Antipsychotic Agents
/
Benzodiazepines
/
Practice Guidelines as Topic
Type of study:
Diagnostic study
/
Practice guideline
/
Prognostic study
/
Systematic review
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
Psychiatry
Year:
2019
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Asociación Psiquiátrica de América Latina (APAL)/BR
/
Associação Brasileira de Psiquiatria/BR
/
Universidade do Sul de Santa Catarina (UNISUL)/BR