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Fatores associados à tuberculose em população de diabéticos: um estudo caso-controle / Factors associated with tuberculosis in a population of diabetics: A case-control study
Leal, Marcelle Lemos; Maciel, Ethel Leonor Nóia; Cade, Nágela Valadão.
Affiliation
  • Leal, Marcelle Lemos; Universidade Federal do Espírito Santo. Centro de Ciências da Saúde. Programa de Pós-Graduação em Saúde Coletiva. Vitória. BR
  • Maciel, Ethel Leonor Nóia; Universidade Federal do Espírito Santo. Centro de Ciências da Saúde. Programa de Pós-Graduação em Saúde Coletiva. Vitória. BR
  • Cade, Nágela Valadão; Universidade Federal do Espírito Santo. Centro de Ciências da Saúde. Programa de Pós-Graduação em Saúde Coletiva. Vitória. BR
Ciênc. Saúde Colet. (Impr.) ; 24(9): 3247-3256, set. 2019. tab
Article in Portuguese | LILACS | ID: biblio-1019674
Responsible library: BR1.1
RESUMO
Resumo Este estudo analisou os fatores associados à tuberculose em diabéticos atendidos nas unidades de saúde de Vitória/ES, Brasil. Trata-se de um estudo caso-controle, sendo 45 casos de diabéticos atendidos nas 30 unidades do município e notificados no SINAN com diagnóstico de tuberculose no período de 2007 a 2013 e 90 de controles diabéticos. Utilizaram-se dados do SINAN, do Sistema de Informação em Saúde de Vitória e do Laboratório Central Municipal, e uma entrevista estruturada. Foram realizadas análises bivariada e multivariada, mediante regressão logística com as variáveis significativas (p < 0,05). O grupo caso apresentou maior frequência de hábitos de vida danosos à saúde em comparação com o grupo controle, como consumo compulsivo de álcool (p < 0,001) e tabagismo (p = 0,060), além de piores parâmetros bioquímicos, como glicemia de jejum (p < 0,001) e hemoglobina glicosilada (p = 0,034). A ingestão regular de bebida alcoólica (OR 6,612; IC 2,151-20,330), o contato prévio com pessoas com tuberculose (OR 4,418; IC 1,678-11,631) e a glicemia de jejum (OR 1,017; IC 1,007-1,026) foram associados à tuberculose nos diabéticos. O estudo revela que piores hábitos de vida e controle glicêmico, e o contato anterior com tuberculose ativa aumentam a chance de o diabético desenvolver tuberculose.
ABSTRACT
Abstract This study analyzed the factors associated with tuberculosis in diabetics seen at health units of Vitória, ES, Brazil. This is a case-control study of 45 cases of diabetics seen in the 30 units of the municipality and reported in the SINAN with a diagnosis of tuberculosis in the 2007-2013 period and 90 cases of diabetic controls. We used data from the SINAN, the Health Information System of Vitória, and the Central Municipal Laboratory, as well a structured interview. Bivariate and multivariate analyses were performed, using logistic regression with the significant variables (p < 0.05). The case group presented a higher frequency of health-damaging life habits as compared to the control group, such as compulsive drinking (p < 0.001) and tobacco smoking (p = 0.060), as well as worse biochemical parameters, such as fasting blood sugar (p < 0.001) and glycosylated hemoglobin (p = 0.034). Regular drinking (OR 6.612, CI 2,151-20.330), previous contact with people with tuberculosis (OR 4.418, CI 1.678-11.631), and fasting blood sugar (OR 1.017, CI 1.007-1.026) were associated with tuberculosis in diabetics. The study reveals that poorer lifestyle habits and glycemic control and previous contact with active tuberculosis increase the chance of diabetics developing tuberculosis.
Subject(s)


Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / Neglected Diseases / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Goal 9: Noncommunicable diseases and mental health / Goal 10: Communicable diseases / Goal 6: Information systems for health / Target 3.3: End transmission of communicable diseases / Target 3.4: Reduce premature mortality due to noncommunicable diseases / Neglected Diseases / Tuberculosis / Alcohol Database: LILACS Main subject: Tuberculosis, Pulmonary / Diabetes Mellitus Type of study: Observational study / Prognostic study / Qualitative research / Risk factors Limits: Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Ciênc. Saúde Colet. (Impr.) Journal subject: Public Health Year: 2019 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Espírito Santo/BR

Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / Neglected Diseases / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Goal 9: Noncommunicable diseases and mental health / Goal 10: Communicable diseases / Goal 6: Information systems for health / Target 3.3: End transmission of communicable diseases / Target 3.4: Reduce premature mortality due to noncommunicable diseases / Neglected Diseases / Tuberculosis / Alcohol Database: LILACS Main subject: Tuberculosis, Pulmonary / Diabetes Mellitus Type of study: Observational study / Prognostic study / Qualitative research / Risk factors Limits: Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Ciênc. Saúde Colet. (Impr.) Journal subject: Public Health Year: 2019 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Espírito Santo/BR
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