Serial 3 dimensional optical coherence tomography assessment of jailed side branch by second-generation drug-eluting absorbable metal scaffold (from the BIOSOLVE-II Trial)
Am. j. cardiol
; 123(7): 1044-1051, Apr. 2019. tab, ilus, graf
Article
in En
| SES-SP, SESSP-IDPCPROD, SES-SP
| ID: biblio-1022205
Responsible library:
BR79.1
Localization: BR79.1
ABSTRACT
Second-generation drug-eluting absorbable metal scaffold (DREAMS 2G) is used for treating coronary lesions. However, the natural history of the jailed side-branch (SB) after DREAMS 2G implantation remains to be elucidated. The aim of this study is to investigate the effect of scaffold struts on jailed SBs as assessed by 3-dimensional (3D) optical coherence tomography (OCT) after implantation of DREAMS 2G. We enrolled the patients who received a DREAMS 2G implantation and where OCT was performed at postprocedure and 12-month follow-up in the BIOSOLVE-II trial. The area of the ostium of jailed SBs and number of compartments divided by scaffold struts were assessed by cut-plane analysis using 3D OCT. A total of 24 patients with 61 jailed SBs were analyzed in this study. The number of compartments was significantly decreased (postprocedure; 1.98 +/- 0.84 vs 12 months; 1.10 +/- 0.30, p <0.001) during the 12 months. Since most of the struts disappeared, the ostium area was increased in 62% of jailed SBs at 12 months, however, not significantly different from postprocedure (postprocedure; 0.74 [0.34 to 1.46] mm(2) vs 12 months; 0.78 [0.41 to 1.68] mm(2), p=0.055). The number of compartments created by scaffold struts and branching angle at postprocedure had no effect on the changes of SB ostium área. DREAMS 2G has a favorable absorption process in the jailed SBs up to 12 months and may be considered as an optional therapy for treating lesions that involve SBs. (AU)
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Collection:
06-national
/
BR
Database:
SES-SP
/
SESSP-IDPCPROD
Main subject:
Coronary Artery Disease
/
Tomography, Optical Coherence
/
Drug-Eluting Stents
Limits:
Humans
Language:
En
Journal:
Am. j. cardiol
Year:
2019
Document type:
Article