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Biofilm formation by blood isolates of candida parapsilosis sensu stricto in the presence of a hyperglycidic solution at comparable concentrations of total parenteral nutrition
Herek, Thalita Caroline; Menegazzo, Vinícius Ribeiro; Ogaki, Mayara Baptistucci; Perini, Hugo Felix; Maia, Luciana Furlaneto; Furlaneto, Marcia Cristina.
Affiliation
  • Herek, Thalita Caroline; Universidade Estadual de Londrina. Departamento de Microbiologia. Londrina. BR
  • Menegazzo, Vinícius Ribeiro; Universidade Estadual de Londrina. Departamento de Ortopedia e Traumatologia. Londrina. BR
  • Ogaki, Mayara Baptistucci; Universidade Estadual de Londrina. Departamento de Microbiologia. Londrina. BR
  • Perini, Hugo Felix; Universidade Estadual de Londrina. Departamento de Microbiologia. Londrina. BR
  • Maia, Luciana Furlaneto; Universidade Tecnológica Federal do Paraná. Departamento de Tecnologia em Alimentos. BR
  • Furlaneto, Marcia Cristina; Universidade Estadual de Londrina. Departamento de Microbiologia. Londrina. BR
Rev. Soc. Bras. Med. Trop ; 52: e20180182, 2019. tab, graf
Article in En | LILACS | ID: biblio-1041508
Responsible library: BR1.1
ABSTRACT
Abstract

INTRODUCTION:

Administration of total parenteral nutrition (TPN) via catheters increases the risk for candidemia from Candida parapsilosis.

METHODS:

C. parapsilosis sensu stricto blood isolates were evaluated for ability total biomass biofilm formation and morphogenesis in presence of glucose at TPN equivalent concentrations.

RESULTS:

Biofilms were increased at high glucose concentrations (25-30%) compared to the control medium. Significant increase in filamentous forms was observed in cultures with 30% glucose.

CONCLUSIONS:

Biofilm formation by C. parapsilosis sensu stricto in hyperglycidic medium may contribute to its pathogenic potential for fungemia related to TPN catheters.
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Biofilms / Candida parapsilosis / Glucose Limits: Humans Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2019 Document type: Article Affiliation country: Brazil Country of publication: Brazil
Fulltext
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Biofilms / Candida parapsilosis / Glucose Limits: Humans Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2019 Document type: Article Affiliation country: Brazil Country of publication: Brazil