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Multidisciplinary diagnostics of chronic lymphocytic leukemia: European Research Initiative on CLL - ERIC recommendations
Zalcberg, Ilana; DAndrea, Mariana Gamma; Monteiro, Lucia; Pimenta, Glicínia; Xisto, Beth.
Affiliation
  • Zalcberg, Ilana; GeneOne. Rio de Janeiro. BR
  • DAndrea, Mariana Gamma; GeneOne. Rio de Janeiro. BR
  • Monteiro, Lucia; GeneOne. Rio de Janeiro. BR
  • Pimenta, Glicínia; GeneOne. Rio de Janeiro. BR
  • Xisto, Beth; Diagnósticos da América. São Paulo. BR
Hematol., Transfus. Cell Ther. (Impr.) ; 42(3): 269-274, July-Sept. 2020. ilus
Article in En | LILACS | ID: biblio-1134046
Responsible library: BR408.1
Localization: BR408.1
ABSTRACT
ABSTRACT Recent advances in chronic lymphocytic leukemia (CLL) includes description of disease genomic landscape, inclusion of prognostic relevant genetic tests in CLL workflow and evaluation of minimal residual disease (MRD)1 in parallel with the increase availability of novel therapy agents.In this review, the theoretical and practical aspects of response assessment have been discussed. These are based on updated recommendations of the European Research Initiative on Chronic Lymphocytic Leukemia (ERIC) for genetic tests (TP53 mutation and IGHV status) and flow cytometry analysis for CLL. Methodological approaches and interpretation of results were also discussed.2,3
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Key words

Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Genes, p53 / Neoplasm, Residual / Flow Cytometry / Mutation Type of study: Diagnostic_studies / Guideline / Prognostic_studies Language: En Journal: Hematol., Transfus. Cell Ther. (Impr.) Journal subject: Hematologia / TransfusÆo de Sangue Year: 2020 Document type: Article Affiliation country: Brazil Country of publication: Brazil

Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Genes, p53 / Neoplasm, Residual / Flow Cytometry / Mutation Type of study: Diagnostic_studies / Guideline / Prognostic_studies Language: En Journal: Hematol., Transfus. Cell Ther. (Impr.) Journal subject: Hematologia / TransfusÆo de Sangue Year: 2020 Document type: Article Affiliation country: Brazil Country of publication: Brazil