The Effect of Sympathomimetic Medication on Cardiovascular Functioning of Children with Attention-Deficit / Hyperactivity Disorder : Cardiovascular Topic
Cardiovasc. j. Afr. (Online)
; 20(5): 296-299, 2009.
Article
in English
| AIM (Africa)
| ID: biblio-1260426
Responsible library:
CG1.1
ABSTRACT
Objective:
The aim of this study was to investigate the effects of sympathomimetic medication on the cardiovascular system of children with attention-deficit / hyperactivity disorder (ADHD).Methods:
Cardiovascular functioning of children with ADHD (n = 19) was tested while the children were stimulant free and during a period in which they were on stimulant medication. Electrocardiograms (ECGs) were obtained by means of a Schiller CardioLaptop AT-110 ECG recorder using the standard 12-lead cable positioning for a resting ECG. Blood pressure was measured by means of a stethoscope and mercury sphygmomanometer.Results:
The main findings of this study were that methylphenidate usage is associated with increases in heart rate (HR) and blood pressure (BP); and that it does not adversely affect HR-corrected QT and JT intervals or cardiac dispersion values.Conclusion:
Methylphenidate causes an increase in HR as well as increases in both systolic and diastolic BP; but no change in cardiac depolarisation and repolarisation duration or homogeneity
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Database:
AIM (Africa)
Main subject:
Attention Deficit Disorder with Hyperactivity
/
Cardiovascular Physiological Phenomena
/
Child
/
Physiological Effects of Drugs
Language:
English
Journal:
Cardiovasc. j. Afr. (Online)
Year:
2009
Document type:
Article