The role of serological testing in the SARS-CoV-2 outbreak
S. Afr. med. j. (Online)
; 0:0(0): 1-4, 2020. ilus
Article
in English
| AIM (Africa)
| ID: biblio-1271064
Responsible library:
CG1.1
ABSTRACT
Antibody tests for the novel coronavirus, SARS-CoV2, have been developed both as rapid diagnostic assays and for high-throughput formal serology platforms. Although these tests may be a useful adjunct to a diagnostic strategy, they have a number of limitations. Because of the antibody and viral dynamics of the coronavirus, their sensitivity can be variable, especially at early time points after symptom onset. Additional data are required on the performance of the tests in the South African population, especially with regard to development and persistence of antibody responses and whether antibodies are protective against reinfection. These tests may, however, be useful in guiding the public health response, providing data for research (including seroprevalence surveys and vaccine initiatives) and development of therapeutic strategies
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Health context:
Sustainable Health Agenda for the Americas
/
SDG3 - Target 3.3 End transmission of communicable diseases
Health problem:
Goal 8: Outbreaks, emergencies and disasters
/
Pneumonia
Database:
AIM (Africa)
Main subject:
South Africa
/
Serologic Tests
/
Public Health
/
Disease Outbreaks
/
Severe acute respiratory syndrome-related coronavirus
/
COVID-19
Type of study:
Diagnostic study
Aspects:
Social determinants of health
Country/Region as subject:
Africa
Language:
English
Journal:
S. Afr. med. j. (Online)
Year:
2020
Document type:
Article