Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
São Paulo med. j
; 139(4): 364-371, Jul.-Aug. 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1290244
Responsible library:
BR1.1
ABSTRACT
ABSTRACT BACKGROUND: Cardiovascular risk factors can mediate the association between depression and cardiovascular diseases. OBJECTIVE: To evaluate cardiovascular risk factors in adult individuals with and without histories of major depression in the metropolitan region of São Paulo, Brazil. DESIGN AND SETTING: Cross-sectional study in São Paulo (SP), Brazil. METHODS: This study evaluated 423 individuals without any lifetime diagnosis of major depression and 203 individuals with a previous diagnosis of major depression (n = 626). The participants underwent a psychiatric evaluation using a structured clinical interview (SCID-1), an anthropometric evaluation and a clinical evaluation that included blood pressure measurement and assessment of fasting blood glucose, lipid profile and physical activity levels. RESULTS: Individuals with histories of major depression were more likely to be female (P < 0.0001). Individuals with lifetime diagnoses of major depression were more likely to be current smokers (odds ratio, OR 1.61; 95% confidence interval, CI 1.01-2.59) and to have diabetes (OR 1.79; 95% CI 1.01-3.21); and less likely to be obese (OR 0.58; 95% CI 0.35-0.94). CONCLUSION: Individuals with major depression had higher odds of presenting tobacco smoking and diabetes, and lower odds of being obese. Healthcare professionals need to be aware of this, so as to increase the rates of diagnosis and treatment in this population.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Cardiovascular Diseases
/
Depressive Disorder, Major
Type of study:
Etiology study
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Observational study
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Prevalence study
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Qualitative research
/
Risk factors
Limits:
Adult
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Female
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Humans
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Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
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Cincia
/
Ginecologia
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Medicine
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Medicina Interna
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Obstetr¡cia
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Pediatria
/
Sa£de Mental
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Sa£de P£blica
Year:
2021
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Center for Clinical and Epidemiological Research, Hospital Universitário (HU), Universidade de Sao Paulo, Sao Paulo, SP, BR, and Full Professor/BR
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Center for Clinical and Epidemiological Research, Hospital Universitário (HU), Universidade de Sao Paulo, Sao Paulo, SP, BR, and Professor, Department of Internal Medicine, Faculdade de Medicina FMUSP/BR
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Department of Public Health/BR
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Postgraduate Program on Collective Health/BR
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Section of Psychiatric Epidemiology (LIM-23), Institute of Psychiatry, Hospital das Clínicas FMUSP, Faculdade de Medicina/BR