Retrospective analysis on efficacy of convalescent plasma in acute respiratory distress syndrome due to COVID-19
São Paulo med. j
; 140(1): 12-16, Jan.-Feb. 2022. tab
Article
in English
| LILACS
| ID: biblio-1357469
Responsible library:
BR1.1
ABSTRACT
ABSTRACT BACKGROUND:
Coronavirus disease 2019 (COVID-19) is an ongoing global health threat. However, currently, no standard therapy has been approved for the disease.OBJECTIVES:
To evaluate the clinical effectiveness of convalescent plasma (CP) in patients with acute respiratory distress syndrome (ARDS) due to COVID-19. DESIGN ANDSETTING:
Retrospective study conducted at Kayseri City Education and Research Hospital, Kayseri, Turkey.METHODS:
The case group consisted of adult patients (> 18 years) with ARDS due to COVID-19 who received CP in combination with antiviral and supportive treatment. These patients were compared with others who only received antiviral and supportive treatment.RESULTS:
During the study period, a total of 30 patients with ARDS due to COVID-19 were included. Eleven patients (36%) received CP in combination with antiviral and supportive treatment, whereas nineteen patients (64%) in the control group only received antiviral and supportive treatment. On admission, the median age, demographic and clinical data and initial laboratory test results were similar between the groups (P > 0.05). On the 14th day of treatment, the laboratory values remained similar between the groups (P > 0.05). The mortality rates were not significantly different between the groups.CONCLUSION:
CP treatment did not affect mortality or lead to clinical improvement for COVID-19 patients with ARDS.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Target 3.8 Achieve universal access to health
/
SDG3 - Health and Well-Being
/
SDG3 - Target 3.3 End transmission of communicable diseases
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Delivery Arrangements
/
Target 3.8 Achieve universal access to health
/
COVID-19
/
Pneumonia
/
Other Respiratory Diseases
Database:
LILACS
Main subject:
Respiratory Distress Syndrome, Newborn
/
COVID-19
Type of study:
Observational study
Limits:
Adult
/
Humans
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
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Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
2022
Document type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
Erciyes Üniversitesi Tip Fakültesi/TR
/
Kayseri City Education and Research Hospital/TR
/
University of Health Sciences/TR