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Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
Celepli, Salih; Çolak, Bayram; Celepli, Pınar; Bigat, İrem; Batur, Hatice Gül; Soysal, Furkan; Karakurt, Serdar; Hücümenoğlu, Sema; Kısmet, Kemal; Şahin, Mustafa.
Affiliation
  • Celepli, Salih; Gülhane Training and Research Hospital. Department of General Surgery. Ankara. TR
  • Çolak, Bayram; Selçuk University. Faculty of Medicine. Department of General Surgery. Konya. TR
  • Celepli, Pınar; Ankara Training and Research Hospital. Department of Pathology. Ankara. TR
  • Bigat, İrem; TOBB University of Economics & Technology. Department of Biomedical Engineering. Ankara. TR
  • Batur, Hatice Gül; Selçuk University. Science Faculty. Biochemistry Department. Konya. TR
  • Soysal, Furkan; Ankara Yıldırım Beyazıt University. Faculty of Engineering and Natural Sciences. Department of Chemical Engineering. Konya. TR
  • Karakurt, Serdar; Selçuk University. Science Faculty. Biochemistry Department. Konya. TR
  • Hücümenoğlu, Sema; Ankara Training and Research Hospital. Department of Pathology. Ankara. TR
  • Kısmet, Kemal; Selçuk University. Faculty of Nursing. Department of Surgical Nursing. Konya. TR
  • Şahin, Mustafa; Selçuk University. Faculty of Medicine. Department of General Surgery. Konya. TR
Rev. Assoc. Med. Bras. (1992, Impr.) ; 68(1): 87-93, Jan. 2022. tab, graf
Article in En | LILACS | ID: biblio-1360707
Responsible library: BR1.1
ABSTRACT
SUMMARY

OBJECTIVE:

The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/reperfusion injury.

METHODS:

Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects. Histopathological findings were scored semiquantitatively.

RESULTS:

Statistically, the antioxidant activity was highest in the artichoke leaf extract group, the difference in biochemical parameters and C-reactive protein was significant compared with the control group, and the histopathological positive effects were found to be significantly higher.

CONCLUSIONS:

As a result, artichoke leaf extract had a hepatoprotective effect and that this effect was related to the antioxidant and anti-inflammatory effects of artichoke.
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Reperfusion Injury / Cynara scolymus Limits: Animals Language: En Journal: Rev. Assoc. Med. Bras. (1992, Impr.) Journal subject: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Year: 2022 Document type: Article Affiliation country: Turkey
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Reperfusion Injury / Cynara scolymus Limits: Animals Language: En Journal: Rev. Assoc. Med. Bras. (1992, Impr.) Journal subject: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Year: 2022 Document type: Article Affiliation country: Turkey