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Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report
Dantas, Kátia Cristina; Freitas, Roseli Santos de; Garcia, Roberta Scholz Pinto; Silva, Marcos Vinícius da; Muricy, Edna Cleide Mendes; Kohara, Valdelene Sayuri; Vicentini, Adriana Pardini.
Affiliation
  • Dantas, Kátia Cristina; University of São Paulo. Medical School. Department of Pathology. São Paulo. BR
  • Freitas, Roseli Santos de; University of São Paulo. Institute of Tropical Medicine. Laboratory of Medical Mycology. São Paulo. BR
  • Garcia, Roberta Scholz Pinto; University of São Paulo. Institute of Tropical Medicine. Laboratory of Medical Mycology. São Paulo. BR
  • Silva, Marcos Vinícius da; Emílio Ribas Infectious Diseases Institute. São Paulo. BR
  • Muricy, Edna Cleide Mendes; University of São Paulo. Institute of Tropical Medicine. Laboratory of Medical Mycology. São Paulo. BR
  • Kohara, Valdelene Sayuri; Adolfo Lutz Institute. Immunology Center. São Paulo. BR
  • Vicentini, Adriana Pardini; Adolfo Lutz Institute. Immunology Center. São Paulo. BR
J. venom. anim. toxins incl. trop. dis ; 20: 1-5, 04/02/2014.
Article in English | LILACS, VETINDEX | ID: biblio-1484590
Responsible library: BR68.1
Localization: BR68.1
ABSTRACT
This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity against Histoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum and Cryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases.
Subject(s)

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Full text: Available Health context: SDG3 - Target 3.3 End transmission of communicable diseases Health problem: Histoplasmosis Database: LILACS / VETINDEX Main subject: Diagnosis / Allergy and Immunology / Histoplasma / Infections Type of study: Diagnostic study / Risk factors Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Year: 2014 Document type: Article Institution/Affiliation country: Adolfo Lutz Institute/BR / Emílio Ribas Infectious Diseases Institute/BR / University of São Paulo/BR
Fulltext
Add to My VHL
Print
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Full text: Available Health context: SDG3 - Target 3.3 End transmission of communicable diseases Health problem: Histoplasmosis Database: LILACS / VETINDEX Main subject: Diagnosis / Allergy and Immunology / Histoplasma / Infections Type of study: Diagnostic study / Risk factors Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Year: 2014 Document type: Article Institution/Affiliation country: Adolfo Lutz Institute/BR / Emílio Ribas Infectious Diseases Institute/BR / University of São Paulo/BR