ARE CALCIUM SILICATE SEALERS LESS CYTOTOXIC AND GENOTOXIC THAN EPOXY RESIN SEALERS? A SYSTEMATIC REVIEW OF IN VITRO STUDIES
J. res. dent
; 11(2): 1-19, Oct 2023.
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1513034
Responsible library:
BR1916.9
ABSTRACT
Aims: This systematic review aimed to evaluate whether calcium silicate-based sealers are less cytotoxicity and genotoxicity than epoxy resin-based sealers. Materials and Methods: Systematic searches were conducted for studies published up to September 27th, 2022, without restriction for language or year of publication, in the following databases: MEDLINE/PubMed, Scopus, Web of Science and Grey Literature Report. Only in vitrostudies that evaluated the cytotoxicity or genotoxicity of calcium silicate and epoxy resin-based sealers were included. The quality assessment was performed. Results: After duplicate removal and eligibility criteria assessment, a total of thirty-four studies were included. Twenty-eight studies had a low risk of bias, and six studies had amoderate risk of bias. In general, calcium silicate-based sealers had a lower cytotoxic and genotoxic potential than epoxy-resin based sealers.Conclusions: Based on the findings from in vitrostudies, calcium silicate-based sealers are less cytotoxic andgenotoxic than epoxy resin-based sealers
Full text:
Available
Collection:
International databases
Database:
LILACS
Type of study:
Systematic review
Language:
English
Journal:
J. res. dent
Journal subject:
Dentistry
/
Sa£de Bucal
Year:
2023
Document type:
Article
Affiliation country:
Brazil