The effect of the anticonvulsants phenobarbital and diphenylhydantoin on intestinal absorption of calcium.
Acta Physiol Lat Am
; 29(4-5): 223-8, 1979.
Article
in En
| BINACIS
| ID: bin-47025
Responsible library:
AR1.1
ABSTRACT
The effect of anticonvulsant drugs (phenobarbital and diphenylhydantoin) on the metabolic balance of calcium and on its intestinal absorption, as measured by an in situ intraluminal perfusion method, was studied in rats. The administration of these drugs produced (a) an increase of the fecal excretion of calcium,. (b) a decrease of the intestinal absorption of calcium (45Ca). Both effects were more intense in rats treated with phenobarbital. There is evidence to suggest that the anticonvulsant drugs affect the intestinal mechanism of active transport of calcium.
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Collection:
06-national
/
AR
Database:
BINACIS
Language:
En
/
Es
Journal:
Acta Physiol Lat Am
/
Acta physiol. latinoam
Year:
1979
Document type:
Article
Country of publication:
Argentina