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Ytterbium-catalyzed formal [4+2] cycloaddition: synthesis of chalcogen-quinolines 3-unsubstituted
Oliveira, Isadora M. de; Darbem, Mariana P; Esteves, Carlos Henrique A; Pimenta, Daniel Carvalho; Zukerman-Schpector, Julio; Stefani, Hélio A; Manarin, Flávia.
Affiliation
  • Darbem, Mariana P; Instituto Butantan. Laboratório de Bioquímica e Biofísica.
Tetrahedron Lett ; 59(44): p. 3907-3911, 2018.
Article in En | SES-SP, SESSP-IBPROD, SES-SP | ID: but-ib15641
Responsible library: BR78.1
Localization: BR78.1
ABSTRACT
A regioselective ytterbium-catalyzed annulation reaction between ethylglyoxalate, anilines and silyl-alkynes bearing selenyl- and telluryl-moieties for the formation of poly-substituted quinolones is described. A series of examples formed under mild conditions are presented, including a scaled-up reaction and a study on catalyst recyclability.
Full text: 1 Collection: 06-national / BR Database: SES-SP / SESSP-IBPROD Language: En Journal: Tetrahedron Lett Year: 2018 Document type: Article
Full text: 1 Collection: 06-national / BR Database: SES-SP / SESSP-IBPROD Language: En Journal: Tetrahedron Lett Year: 2018 Document type: Article