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Early stage breast cancer conserving treatment: high dose rate brachytherapy boost to the tumour bed
López Carrizosa, María Concepción; Samper Ots, Pilar María; Vallejo Ocaña, Carmen; Aurora Rodríguez Pérez, Aurora; Sáez Garrido, Juan de Dios; Delgado Pérez, José María.
Affiliation
  • López Carrizosa, María Concepción; Hospital Central de la Defensa. Madrid. España
  • Samper Ots, Pilar María; Hospital Central de la Defensa. Madrid. España
  • Vallejo Ocaña, Carmen; Hospital Central de la Defensa. Madrid. España
  • Aurora Rodríguez Pérez, Aurora; Hospital Central de la Defensa. Madrid. España
  • Sáez Garrido, Juan de Dios; Hospital Central de la Defensa. Madrid. España
  • Delgado Pérez, José María; Hospital Central de la Defensa. Madrid. España
Clin. transl. oncol. (Print) ; 7(8): 344-350, sept. 2005. tab, graf
Article in En | IBECS | ID: ibc-040785
Responsible library: ES1.1
Localization: ES1.1 - BNCS
ABSTRACT
Introduction. The dose administered to the tumour bed is a risk-factor for local recurrence in localised breast cancer following breast-conserving surgery. Materials and Methods. All patients (n=94) received 50 Gy external beam radiotherapy and one application of 700 cGy at 85% isodose with high dose rate brachytherapy. Results. Of the cases, 84% were infiltrating ductal carcinoma; 31.2% were G3; 28% were intraductal component > 25%; 54% had margin 3 cm (p = 0.001), irradiation volume with external beam radiotherapy (p = 0.0001), and presence of local recurrence (p = 0.001). Conclusion. High dose rate brachytherapy is an effective method for reducing local recurrence, and increasing local control
Subject(s)
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Collection: 06-national / ES Database: IBECS Main subject: Radiotherapy / Breast Neoplasms / Neoplasm Recurrence, Local Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Clin. transl. oncol. (Print) Year: 2005 Document type: Article
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Collection: 06-national / ES Database: IBECS Main subject: Radiotherapy / Breast Neoplasms / Neoplasm Recurrence, Local Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Clin. transl. oncol. (Print) Year: 2005 Document type: Article