Malignant lymphoma of the oral cavity and the maxillofacial region: Overall survival prognostic factors
Med. oral patol. oral cir. bucal (Internet)
; 18(4): 619-626, jul. 2013. ilus, tab
Article
in English
| IBECS
| ID: ibc-114483
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Objective:
To identify the overall survival and prognostic factors of malignant lymphoma of the oral cavity and the maxillofacial region. StudyDesign:
Clinical records data were obtained in order to determine overall survival at 2 and 5 years, the individual survival percentage of each possible prognostic factor with the actuarial technique, and the survival regarding the possible prognostic factors with the actuarial technique and the Log-rank and Cox's regression tests.Results:
Of 151 subjects, an overall survival was 60% at 2 years, and 45% at 5 years. The multivariate analysis demonstrated statistically significant differences for clinical stage (p=0.002), extranodal involvement (p=0.030), presence of human immunodeficiency virus (p=0.032), and presence of Epstein-Barr virus (p=0.010).Conclusion:
The advanced clinical stage and the larger number of involved extranodular sites are related to a lower overall survival, as well as, the presence of previous infections such as the human immunodeficiency and the Epstein-Barr virus (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Mouth Neoplasms
/
Maxillary Neoplasms
/
Lymphoma
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Med. oral patol. oral cir. bucal (Internet)
Year:
2013
Document type:
Article
Institution/Affiliation country:
Federal University of Juiz de Fora/Brazil
/
Hospital A.C. Camargo/Brazil
/
National Institute for Neoplastic Diseases/Peru
/
Peruvian University Cayetano Heredia/Peru
/
USMP/Peru