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Prevalence of Asthma and Severity of Allergic Rhinitis Comparing 2 Perennial Allergens: House Dust Mites and Parietaria judaica Pollen
Sala-Cunill, A; Bartra, J; Dalmau, G; Tella, R; Botey, E; Raga, E; Valero, A.
Affiliation
  • Sala-Cunill, A; Hospital Universitari Vall d'Hebron. Internal Medicine Department. Barcelona. Spain
  • Bartra, J; Hospital Clinic-IDIBAPS. Pneumology and Allergy Department. Barcelona. Spain
  • Dalmau, G; Hospital Universitari Joan XIII. Allergy Unit. Tarragona. Spain
  • Tella, R; Hospital Universitari Josep Trueta. Allergy Unit. Girona. Spain
  • Botey, E; Hospital Universitari Dexeus. Allergy Unit. Spain
  • Raga, E; Hospital Plató. Allergy Unit. Barcelona. Spain
  • Valero, A; Hospital Clinic-IDIBAPS. Pneumology and Allergy Department. Barcelona. Spain
J. investig. allergol. clin. immunol ; 23(3): 145-151, mayo-jun. 2013. tab
Article in English | IBECS | ID: ibc-114857
Responsible library: ES1.1
Localization: BNCS
RESUMEN
Antecedentes La rinitis alérgica (RA) es una enfermedad de prevalencia creciente en todo el mundo, con un importante impacto en la calidad de vida, generando un elevado coste sanitario. La rinitis y el asma pueden ser consideradas como parte de una misma enfermedad y por tanto, la RA puede conducir a un incremento del riesgo de desarrollar asma.

Objetivos:

Evaluar la prevalencia de asma en pacientes con RA por ácaros del polvo doméstico (APD) y en pacientes con RA por Parietaria judaica y evaluar las características de la rinitis y del asma en cada grupo.

Métodos:

Estudio multicéntrico, transversal. Se registraron las características demográficas y clínicas de todos los pacientes. Todos los pacientes tenían RA confirmada por síntomas y pruebas positivas a APD o a Parietaria judaica. Los pacientes se clasificaron según la gravedad y la frecuencia de la rinitis siguiendo los criterios del ARIA y ARIA modificada y la gravedad del asma según los criterios de la GINA.

Resultados:

Se incluyeron un total de 395 pacientes, 226 en el grupo de APD y 169 en el grupo de la Parietaria judaica, con una media de edad de 43±15,3 años. La clasificación ARIA modificada nos permitió detectar que el grupo de Parietaria presentaba una rinitis más persistente y grave comparado con el grupo de APD (44,5% versus 24,8%, p<0,001). Sin embargo, no se obtuvieron diferencias estadísticamente significativas entre la gravedad y la prevalencia (50% en APD vs 47,9% en Parietaria, p=0,685) del asma en los dos grupos.

Conclusiones:

La RA por polen de Parietaria judaica, que se comporta como un alérgeno perenne, puede causar la misma prevalencia de asma y una rinitis más grave que APD (AU)
ABSTRACT

Background:

Allergic rhinitis (AR) is an increasingly prevalent worldwide disease that has a considerable impact on quality of life and health care costs. Asthma and AR may be part of the same disease, with AR leading to an increased risk of asthma.

Objectives:

To assess the prevalence of asthma in patients with AR due to house dust mites (HDMs) or Parietaria judaica and analyze the characteristics of asthma and AR in each group.

Methods:

Cross-sectional, multicenter study with recording of demographic and clinical characteristics. All patients had AR confirmed by symptoms and a positive skin prick test to HDMs or P judaica. They were classified according to the severity and frequency of AR following the Allergic Rhinitis and its Impact on Asthma (ARIA) and modified ARIA criteria and according to the severity of asthma following the Global Initiative for Asthma criteria.

Results:

We studied 395 patients (226 in the HDM group and 169 in the P judaica group) with a mean (SD) age of 43 (15.3) years. Using the modified ARIA criteria, we detected more severe and persistent AR in the P judaica group than in the HDM group (44.5% vs 24.8%, P<.001). Nevertheless, there were no statistically significant differences between the groups in terms of the severity or prevalence (50% in HDM vs 47.9% in P judaica, P=.685) of asthma.

Conclusion:

AR due to P judaica pollen, which behaves like a perennial allergen, is associated with the same prevalence of asthma and with more severe rhinitis than AR due to HDMs (AU)
Subject(s)
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Collection: National databases / Spain Database: IBECS Main subject: Asthma / Rhinitis / Rhinitis, Allergic, Seasonal / Hypersensitivity, Immediate Type of study: Controlled clinical trial / Prevalence study / Risk factors Aspects: Patient-preference Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: J. investig. allergol. clin. immunol Year: 2013 Document type: Article Institution/Affiliation country: Hospital Clinic-IDIBAPS/Spain / Hospital Plató/Spain / Hospital Universitari Dexeus/Spain / Hospital Universitari Joan XIII/Spain / Hospital Universitari Josep Trueta/Spain / Hospital Universitari Vall d'Hebron/Spain
Search on Google
Collection: National databases / Spain Database: IBECS Main subject: Asthma / Rhinitis / Rhinitis, Allergic, Seasonal / Hypersensitivity, Immediate Type of study: Controlled clinical trial / Prevalence study / Risk factors Aspects: Patient-preference Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: J. investig. allergol. clin. immunol Year: 2013 Document type: Article Institution/Affiliation country: Hospital Clinic-IDIBAPS/Spain / Hospital Plató/Spain / Hospital Universitari Dexeus/Spain / Hospital Universitari Joan XIII/Spain / Hospital Universitari Josep Trueta/Spain / Hospital Universitari Vall d'Hebron/Spain
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