A patient with breast cancer with hepatic metastases and a complete response to herceptin as monotherapy
Clin. transl. oncol. (Print)
; 8(10): 761-763, oct. 2006. ilus
Article
in English
| IBECS
| ID: ibc-125326
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
The majority of deaths due to breast cancer occur in the context of complications secondary to metastatic disease. Trastuzumab, as a second line treatment, has shown a 15% objective response rate in patients with metastatic breast cancer. We present the case of a patient with two breast tumours, the second of more aggressive characteristics, with negative hormone receptors and c-erb-B2 +++, and with few therapeutic options due to her hepatic insufficiency secondary to metastatic disease; she was administered herceptin as monotherapy, and she had a complete clinical response. Trastuzumab has revolutionised the management of patients with metastatic breast cancer and Her-2- neu overexpression. Its combination with chemotherapy agents achieves a synergic activity (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Bone Neoplasms
/
Breast
/
Antineoplastic Combined Chemotherapy Protocols
/
Antineoplastic Agents, Hormonal
/
Antibodies, Monoclonal
/
Antineoplastic Agents
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2006
Document type:
Article
Institution/Affiliation country:
Elche University General Hospital/Spain