Comparing CTVs for permanent prostate brachytherapy
Clin. transl. oncol. (Print)
; 17(5): 393-397, mayo 2015. ilus, tab
Article
in English
| IBECS
| ID: ibc-141721
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Background and purpose:
To delineate the clinical target volume (CTV) in low dose rate (LDR) brachytherapy for prostate cancer, American Brachytherapy Society (ABS) recommends a CTV = prostate. ESTRO advocates a CTV = prostate + 3 mm excluding rectum and many authors use and recommend other different CTVs. This study aims to (1) evaluate the appropriateness of these recommendations and (2) test the applicability of seed distributions on the different CTVs and contrast the dosimetric differences. Materials andmethods:
Ninety-eight patients treated with 125I seeds (dose 145 Gy; CTV = prostate) were studied. We established for every patient (1) risk of extraprostatic extension (EPE), (2) adequacy of original plan to an extended CTV with 3 mm-margin (3) a new planning and seed distribution for this CTV and (4) comparison of dosimetry of both plans.Results:
Mean risk of EPE was 28.46 %. Original plan, when applied to the extended CTV, resulted in unsatisfactory dosimetry. A plan was generated for the 98 extended CTVs meeting all dosimetric specifications.Conclusions:
The risk of EPE is high enough to consider a 3 mm-margin around prostate necessary for all cases. A CTV = prostate + 3 mm except rectum as ESTRO recommends is feasible and would adjust planning to the most probable extension of the tumor (AU)RESUMEN
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Collection:
National databases
/
Spain
Health context:
Sustainable Health Agenda for the Americas
/
SDG3 - Health and Well-Being
Health problem:
Goal 9: Noncommunicable diseases and mental health
/
Target 3.4: Reduce premature mortality due to noncommunicable diseases
Database:
IBECS
Main subject:
Prognosis
/
Prostatic Neoplasms
/
Brachytherapy
Type of study:
Practice guideline
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2015
Document type:
Article
Institution/Affiliation country:
University of La Laguna Tenerife/Spain