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Concentración de interleuquina-6 en el vítreo de pacientes con desprendimiento de retina / Interleukin-6 concentrations in the vitreous body of patients with retinal detachment
Asensio-Sánchez, VM; Collazos, JM; Cantón, J.
Affiliation
  • Asensio-Sánchez, VM; Hospital Clínico Universitario. Servicio de Oftalmología. Valladolid. España
  • Collazos, JM; Hospital Medina del Campo. Servicio de Bioquímica. Valladolid. España
  • Cantón, J; Hospital Medina del Campo. Servicio de Bioestadística. Valladolid. España
Arch. Soc. Esp. Oftalmol ; 90(11): 527-530, nov. 2015. tab
Article in Es | IBECS | ID: ibc-145383
Responsible library: ES1.1
Localization: BNCS
RESUMEN

OBJETIVO:

Determinar los niveles de interleuquina-6 (IL-6) en el vítreo de pacientes con desprendimiento de retina (DdR). MATERIAL Y

MÉTODO:

Mediante vitrectomía vía pars plana, se recogieron muestras no diluidas de vítreo de 40 pacientes sin antecedentes de cirugía vítrea o intraocular previa, que fueron divididos en 2 grupos A (n = 20) pacientes con DdR y B (n = 20) pacientes con membrana premacular y agujero macular. La concentración de IL-6 se determinó mediante radioinmunoensayo.

RESULTADOS:

La concentración vítrea de IL-6 en el grupo A fue 122,4 + -16 pg/mL (rango 91,5-620) y en el grupo B fue 46 +/- 23 pg/mL (rango 3-150) (p < 0,001).

CONCLUSIONES:

Estos resultados demuestran que la concentración vítrea de IL-6 está más elevada en los pacientes con DdR en comparación con el grupo control
ABSTRACT

OBJECTIVE:

To measure interleuquin-6 (IL-6) levels in the vitreous body of patients with retinal detachment (RD). PATIENTS AND

METHODS:

Undiluted vitreous samples were obtained from 40 patients with no history of prior vitreous or intraocular surgery. Patients were divided into two groups A (n = 20) patients with RD and B (n = 20) patients with pre-retinal macular membranes and macular holes. IL-6 was determined using radioimmunoassay.

RESULTS:

IL-6 vitreous concentration in group A was 122.4 + -16 pg/mL (range 91.5-620) and in group B was 46 +/- 23 pg/mL (range 3-150) (p < .001).

CONCLUSIONS:

These results show that the concentration of IL-6 in the vitreous body was significantly higher in patients with RD than in the control group
Subject(s)
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Collection: 06-national / ES Database: IBECS Main subject: Retinal Perforations / Vitrectomy / Retinal Detachment / Optic Nerve Diseases / Hematopoietic Cell Growth Factors / Receptors, Interleukin-6 / Informed Consent Type of study: Diagnostic_studies / Evaluation_studies / Prognostic_studies Limits: Female / Humans / Male Language: Es Journal: Arch. Soc. Esp. Oftalmol Year: 2015 Document type: Article
Search on Google
Collection: 06-national / ES Database: IBECS Main subject: Retinal Perforations / Vitrectomy / Retinal Detachment / Optic Nerve Diseases / Hematopoietic Cell Growth Factors / Receptors, Interleukin-6 / Informed Consent Type of study: Diagnostic_studies / Evaluation_studies / Prognostic_studies Limits: Female / Humans / Male Language: Es Journal: Arch. Soc. Esp. Oftalmol Year: 2015 Document type: Article
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