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Genomic Plasticity of Vibrio cholerae
Escudero, Jose Antonio; Mazel, Didier.
Affiliation
  • Escudero, Jose Antonio; Universidad Complutense Madrid. Health Surveillance Centre. Madrid. Spain
  • Mazel, Didier; Universidad Complutense de Madrid. Facultad de Veterinaria. Departamento de Sanidad Animal. Madrid. Spain
Int. microbiol ; 20(3): 138-148, sept. 2017. ilus
Article in En | IBECS | ID: ibc-171332
Responsible library: ES1.1
Localization: BNCS
ABSTRACT
Vibrio cholerae is one of the deadliest pathogens in the history of humankind. It is the causative agent of cholera, a disease characterized by a profuse and watery diarrhoea that still today causes 95.000 deaths worldwide every year. V. cholerae is a free living marine organism that interacts with and infects a variety of organisms, from amoeba to humans, including insects and crustaceans. The complexity of the lifestyle and ecology of V. cholerae suggests a high genetic and phenotypic plasticity. In this review, we will focus on two peculiar genomic features that enhance genetic plasticity in this bacterium: the division of its genome in two different chromosomes and the presence of the superintegron, a gene capture device that acts as a large, low-cost memory of adaptive functions, allowing V. cholerae to adapt rapidly (AU)
RESUMEN
No disponible
Subject(s)

Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Vibrio cholerae / Cholera / Prokaryotic Initiation Factors / Diarrhea Type of study: Etiology_studies Limits: Female / Humans / Male Language: En Journal: Int. microbiol Year: 2017 Document type: Article

Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Vibrio cholerae / Cholera / Prokaryotic Initiation Factors / Diarrhea Type of study: Etiology_studies Limits: Female / Humans / Male Language: En Journal: Int. microbiol Year: 2017 Document type: Article