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Antiplatelet therapy in patients undergoing oral surgery: A systematic review and meta-analysis
Villanueva, Julio; Salazar, Josefina; Alarcón, Ana; Araya, Ignacio; Yanine, Nicolás; Domancic, Stefan; Carrasco-Labra, Alonso.
Affiliation
  • Villanueva, Julio; University of Chile. Cochrane Associated Center at School of Dentistry. Oral & Maxillofacial Department. Chile
  • Salazar, Josefina; University of Chile. Cochrane Associated Center at School of Dentistry. Oral & Maxillofacial Department. Chile
  • Alarcón, Ana; University of Chile. Cochrane Associated Center at School of Dentistry. Oral & Maxillofacial Department. Chile
  • Araya, Ignacio; University of Chile. Cochrane Associated Center at School of Dentistry. Oral & Maxillofacial Department. Chile
  • Yanine, Nicolás; University of Chile. Cochrane Associated Center at School of Dentistry. Oral & Maxillofacial Department. Chile
  • Domancic, Stefan; University of Chile. Cochrane Associated Center at School of Dentistry. Oral & Maxillofacial Department. Chile
  • Carrasco-Labra, Alonso; Mc Master University. Department of Health Research methodology Evidence and Impact. Halmilton. Canada
Med. oral patol. oral cir. bucal (Internet) ; 24(1): e103-e113, ene. 2019. tab, graf
Article in En | IBECS | ID: ibc-180413
Responsible library: ES1.1
Localization: BNCS
ABSTRACT
Background: The number of patients under antiplatelet therapy (APT) continues to raise as current recommendations foster this practice. Although some recommendations to manage this treatment during oral surgery procedures exist, these have methodological shortcomings that preclude them from being conclusive. Material and Methods: A systematic review and meta-analysis of the best current evidence was carried out; The Cochrane Library, EMBASE and MEDLINE databases were searched for Randomized Controlled Trials (RCT) concerning patients undergoing oral surgery with APT, other relevant sources were searched manually. Results: 5 RCTs met the Inclusion criteria. No clear tendency was observed (RR= 0.97 CI 95%: 0,41-2,34; p=0,09; I2= 51%), moreover, they weren't clinically significant. Conclusions: According to these findings and as bleeding is a manageable complication it seems unreasonable to undermine the APT, putting the patient in danger of a thrombotic event and its high inherent morbidity, which isn’t comparable in severity and manageability to the former"
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Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Platelet Aggregation Inhibitors / Oral Surgical Procedures Limits: Humans Language: En Journal: Med. oral patol. oral cir. bucal (Internet) Year: 2019 Document type: Article
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Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Platelet Aggregation Inhibitors / Oral Surgical Procedures Limits: Humans Language: En Journal: Med. oral patol. oral cir. bucal (Internet) Year: 2019 Document type: Article