Fecal microbiota transplantation in the intestinal decolonization of carbapenamase-producing enterobacteriaceae
Rev. esp. enferm. dig
; 112(12): 925-928, dic. 2020. tab, graf
Article
in En
| IBECS
| ID: ibc-200581
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
BACKGROUND AND AIMS:
fecal microbiota transplantation (FMT) is effective for recurrent Clostridium difficile infection (CDI). Intestinal decolonization of carbapenamase-producing enterobacteriaceae (CPE) can prevent transmission and infection by these agents. The aim of this study was to assess CPE decolonization after FMT.METHODS:
this was a case-series study that consecutively included all CPE-carriers that underwent FMT between 2014 and 2019. The indications included refractory/recurrent CDI and CPE-decolonization.RESULTS:
out of 21 CPE-carriers, eight were excluded due to incomplete post-FMT testing. CPE decolonization was confirmed in 76.9 % (n = 10). The median decolonization time was 16-weeks (IQR-23) and ranged from two to 53 weeks.CONCLUSION:
FMT may be used in the clinical practice for CPE-decolonization as an alternative to combined antibiotic regimensRESUMEN
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Collection:
06-national
/
ES
Database:
IBECS
Main subject:
Enterobacteriaceae Infections
/
Dysbiosis
/
Fecal Microbiota Transplantation
/
Carbapenem-Resistant Enterobacteriaceae
/
Intestines
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
En
Journal:
Rev. esp. enferm. dig
Year:
2020
Document type:
Article