IgA Vasculitis involving four systems / Vasculitis IgA que afecta a cuatro sistemas

ABSTRACT

Henoch-Schonlein Purpura (HSP) is a systemic vasculitis now called IgA vasculitis, that infrequently occurs in adults. While rheumatological andgastrointestinal complications are common, lung involvement is a rare complication. We report the case of a 70 year-old female that presented tothe hospital with purpuric lesions on her legs and ileitis. During her hospital stay she developed respiratory distress, and the computed tomography (CT scan) showed evidence of Diffuse Alveolar Hemorrhage (DAH). She also had renal dysfunction, and the renal biopsy confirmed the presence of leukocytoclastic vasculitis on histology, consistent with HSP. The patient was initiated on corticosteroid therapy and cyclophosphamide,in addition to supportive management, leading to the resolution of her symptoms.This case is unique, as it presents a rare complication of HSP, with pulmonary disease, causing DAH. Furthermore, adult onset HSP is also anuncommon occurrence.It is very important to recognize DAH early in HSP, as it holds a high mortality rate. (AU)