The role of hyperbaric oxygen therapy in the treatment of radiation lesions
Clin. transl. oncol. (Print)
; 24(12): 2466-2474, dec. 2022.
Article
in En
| IBECS
| ID: ibc-216092
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Introduction Cancer remains one of the leading causes of death worldwide, with 5060% of patients requiring radiotherapy during the course of treatment. Patients survival rate has increased significantly, with an inevitable increase in the number of patients experiencing side effects from cancer therapy. One such effect is late radiation injuries in which hyperbaric oxygen therapy appears as complementary treatment. With this work we intend to divulge the results of applying hyperbaric oxygen therapy among patients presenting radiation lesions in our Hyperbaric Medicine Unit.Materials and methods Retrospective analysis of clinical records of patients with radiation lesions treated at the Hyperbaric Medicine Unit assessed by the scale Late Effects of Normal TissuesSubjective, Objective, Management, Analytical (LENT-SOMA) before and after treatment, between October 2014 and September 2019 were included. Demographic characteristics, primary tumor site, subjective assessment of the LENT-SOMA scale before and after treatment were collected and a comparative analysis (Students t test) was done. Results 88 patients included 33 with radiation cystitis, 20 with radiation proctitis, 13 with osteoradionecrosis of the mandible and 22 with radiation enteritis. In all groups, there was a significant decrease (p < 0.005) in the subjective parameter of the LENT-SOMA scale. Discussion Late radiation lesions have a major influence on patients quality of life. In our study hyperbaric oxygen therapy presents as an effective therapy after the failure of conventional treatments. Conclusion Hyperbaric oxygen therapy is an effective complementary therapy in the treatment of refractory radiation lesions. (AU)
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Collection:
06-national
/
ES
Database:
IBECS
Main subject:
Radiation Injuries
/
Hyperbaric Oxygenation
Limits:
Humans
Language:
En
Journal:
Clin. transl. oncol. (Print)
Year:
2022
Document type:
Article