Circular RNAs: characteristics, functions, mechanisms, and potential applications in thyroid cancer / ARN circulares: características, funciones, mecanismos y posibles aplicaciones en el cáncer de tiroides
Clin. transl. oncol. (Print)
; 26(4): 808-824, Abr. 2024. ilus
Article
in En
| IBECS
| ID: ibc-VR-45
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Thyroid cancer (TC) is one of the most common endocrine malignancies, and its incidence has increased globally. Despite extensive research, the underlying molecular mechanisms of TC remain partially understood, warranting continued exploration of molecular markers for diagnostic and prognostic applications. Circular RNAs (circRNAs) have recently garnered significant attention owing to their distinct roles in cancers. This review article introduced the classification and biological functions of circRNAs and summarized their potential as diagnostic and prognostic markers in TC. Further, the interplay of circRNAs with PI3K/Akt/mTOR, Wnt/β-catenin, MAPK/ERK, Notch, JAK/STAT, and AMPK pathways is elaborated upon. The article culminates with an examination of circRNA's role in drug resistance of TC and highlights the challenges in circRNA research in TC.(AU)
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Collection:
06-national
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ES
Database:
IBECS
Main subject:
Spine
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Postoperative Care
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Postoperative Period
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Poverty
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Arthrodesis
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Psychology, Educational
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Rehabilitation
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Short Bowel Syndrome
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Spinal Injuries
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General Surgery
Type of study:
Clinical_trials
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Guideline
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Observational_studies
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Prognostic_studies
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Screening_studies
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Systematic_reviews
Aspects:
Determinantes_sociais_saude
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Patient_preference
Limits:
Humans
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Female
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Male
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Adolescent
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Adult
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Child
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Aged
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Infant
Country/Region as subject:
Europa
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America do sul
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Africa
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Brasil
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Peru
Language:
Es
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En
Journal:
An. pediatr. (2003. Ed. impr.)
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An. sist. sanit. Navar
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Aten. prim. (Barc., Ed. impr.)
/
Clin. transl. oncol. (Print)
/
Int. microbiol
/
Nutr. clín. diet. hosp
/
Nutr. hosp
/
Rehabilitación (Madr., Ed. impr.)
/
Rev. Soc. Andal. Traumatol. Ortop. (Ed. impr.)
/
Rev. esp. anestesiol. reanim
Year:
2023
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2022
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2021
/
2024
Document type:
Article