Antigenic and genomic characterization of adenovirus associated to respiratory infections in children living in Northeast Brazil
Mem. Inst. Oswaldo Cruz
; 102(8): 937-941, Dec. 2007. ilus
Article
in En
| LILACS
| ID: lil-471860
Responsible library:
BR1.1
ABSTRACT
From January to December 1998, nasopharyngeal aspirates were obtained from 482 children with acute respiratory infections attended in emergence department and wards of a teaching hospital in the city of Salvador, Brazil. The samples were tested for the presence of adenovirus by isolation in tissue culture and indirect immunofluorescence assay. Eleven adenoviruses were detected by both methods in the same clinical samples. Infections by adenovirus were observed during seven months of the year without association with rainy season. Genome analysis was performed on these 11 isolates. Species C was represented by serotypes 1, 2 and 5. Within species B, only serotype 7 (Ad7) was detected. Two genomic variants of Ad1, two variants of Ad2, one of Ad5, and one of Ad7 (7h) were identified. This is the first study of molecular epidemiology of adenovirus associated to acute respiratory infections in children living in Northeast Brazil, and contributes to a better understanding of adenovirus infections in the country.
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Respiratory Tract Infections
/
Adenovirus Infections, Human
/
Adenoviruses, Human
Type of study:
Risk_factors_studies
Limits:
Child
/
Humans
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Mem Inst Oswaldo Cruz
/
Mem. Inst. Oswaldo Cruz
/
Mem. Inst. Oswaldo Cruz (Online)
/
Memórias do Instituto Oswaldo Cruz (Impresso)
/
Proceedings of the Instituto Oswaldo Cruz
Journal subject:
MEDICINA TROPICAL
/
PARASITOLOGIA
Year:
2007
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil