Narrowing the gap of personalized medicine in emerging countries: the case of multiple endocrine neoplasias in Brazil
Clinics
; 67(supl.1): 3-6, 2012.
Article
in En
| LILACS
| ID: lil-623123
Responsible library:
BR1.1
ABSTRACT
The finished version of the human genome sequence was completed in 2003, and this event initiated a revolution in medical practice, which is usually referred to as the age of genomic or personalized medicine. Genomic medicine aims to be predictive, personalized, preventive, and also participative (4Ps). It offers a new approach to several pathological conditions, although its impact so far has been more evident in mendelian diseases. This article briefly reviews the potential advantages of this approach, and also some issues that may arise in the attempt to apply the accumulated knowledge from genomic medicine to clinical practice in emerging countries. The advantages of applying genomic medicine into clinical practice are obvious, enabling prediction, prevention, and early diagnosis and treatment of several genetic disorders. However, there are also some issues, such as those related to (a) the need for approval of a law equivalent to the Genetic Information Nondiscrimination Act, which was approved in 2008 in the USA; (b) the need for private and public funding for genetics and genomics; (c) the need for development of innovative healthcare systems that may substantially cut costs (e.g. costs of periodic medical followup); (d) the need for new graduate and postgraduate curricula in which genomic medicine is emphasized; and (e) the need to adequately inform the population and possible consumers of genetic testing, with reference to the basic aspects of genomic medicine.
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Multiple Endocrine Neoplasia
/
Thyroid Neoplasms
/
Genetic Testing
/
Carcinoma, Medullary
/
Delivery of Health Care
/
Precision Medicine
/
Mutation
Type of study:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Aspects:
Determinantes_sociais_saude
Limits:
Humans
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Clinics
Journal subject:
MEDICINA
Year:
2012
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil