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Simultaneous presence of bovine papillomavirus and bovine leukemia virus in different bovine tissues: in situ hybridization and cytogenetic analysis
Yaguiu, A; Dagli, M. L. Z; Birgel Jr, E. H; Alves Reis, B. C. A; Ferraz, O. P; Pituco, E. M; Freitas, A. C; Beçak, W; Stocco, R. C.
Affiliation
  • Yaguiu, A; Instituto Butantan. Laboratório de Genética. São Paulo. BR
  • Dagli, M. L. Z; Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Patologia. São Paulo. BR
  • Birgel Jr, E. H; Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Clínica Médica. São Paulo. BR
  • Alves Reis, B. C. A; Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Imunologia. São Paulo. BR
  • Ferraz, O. P; Instituto Butantan. Laboratório de Genética. São Paulo. BR
  • Pituco, E. M; Instituto Biológico. Laboratório de Viroses de Bovídeos. São Paulo. BR
  • Freitas, A. C; Universidade Federal de Pernambuco. Departamento de Genética. Recife. BR
  • Beçak, W; Instituto Butantan. Laboratório de Genética. São Paulo. BR
  • Stocco, R. C; Instituto Butantan. Laboratório de Genética. São Paulo. BR
Genet. mol. res. (Online) ; Genet. mol. res. (Online);7(2): 487-497, 2008. ilus
Article in En | LILACS | ID: lil-640989
Responsible library: BR26.1
ABSTRACT
Bovine papillomavirus (BPV) DNA sequences were detected in different tissues, in addition to epithelium. Cytogenetic abnormalities were observed in blood lymphocytes. The presence of more than one virus in a single tissue is a difficult aspect to evaluate, especially when the DNA sequences are detected in tissues that are not specifically targeted by the virus. BPV and bovine leukemia virus (BLV) are clastogenic, causing chromosome aberrations in peripheral blood lymphocytes. In the present study, we investigated the simultaneous presence of DNA sequences of both viruses and the possibility of vertical transmission and compared the types of chromosome aberrations related to viral action. BPV 1, 2, and 4 DNA sequences were found in three females of the herd and in their offspring. BLV DNA sequences were not detected in their progeny. A newborn calf that was negative for BLV infection showed specific chromosome rearrangements possibly related to the effect of infection with BPV.
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: In Situ Hybridization / Leukemia Virus, Bovine / Cytogenetic Analysis / Bovine papillomavirus 1 Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Genet. mol. res. (Online) Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2008 Document type: Article / Project document Affiliation country: Brazil Country of publication: Brazil

Full text: 1 Collection: 01-internacional Database: LILACS Main subject: In Situ Hybridization / Leukemia Virus, Bovine / Cytogenetic Analysis / Bovine papillomavirus 1 Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Genet. mol. res. (Online) Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2008 Document type: Article / Project document Affiliation country: Brazil Country of publication: Brazil